Frequently Asked Questions (FAQs) about Megace ES

Who should take Megace ES?

Megace ES is approved by the FDA for the treatment of appetite loss, severe malnutrition, or unexplained, significant weight loss in AIDS patients.¹

How do I know if my weight loss is a serious problem?

You can use our self-assessment survey to help facilitate a conversation with your healthcare provider about your weight. If you are concerned about your weight, talk to your healthcare provider.

How much Megace ES should I take?

The recommended dose of Megace ES is 1 teaspoon once daily (1 teaspoon = 625 mg/5 mL).¹ Be sure to take Megace ES only as directed by your healthcare provider.

Can I take Megace ES at any time during the day?

Yes, Megace ES can be taken at any time of the day. It is a good idea to link the time to something else you do every day and then stick with it, making it less likely that you will forget a dose. For example, you could take Megace ES once a day when you wake up. Always take Megace ES as directed by your healthcare provider.

Do I have to eat before I take Megace ES?

No, it is not necessary to take Megace ES with food.

What does Megace ES taste like?

Megace ES has a lemon-lime flavor.¹

What side effects could occur while taking Megace ES?

Side effects related to Megace ES, and occurring more commonly than with a sugar pill, include passing gas, rash, high blood pressure, fever, decreased sexual desire, not being able to have or keep an erection during sex, difficulty falling asleep, upset stomach, and increased blood sugar. Women may experience spotting between periods.

Reports of a blood clot forming in a blood vessel have been linked with use of Megace ES. If you have a history of blood clots, you should contact your doctor before using Megace ES.

With long term use of megestrol acetate, development and worsening of diabetes, Cushing’s Syndrome (which may be recognized by weight gain in the midsection or upper back, rounding of the face, weakness, tiredness, high blood pressure, and bruising), and adrenal insufficiency (which may be recognized by low blood pressure, upset stomach, vomiting, dizziness, or weakness) have been reported.

Be sure to tell your doctor if you experience any side effects while taking Megace ES. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.FDA.gov/medwatch, or call 1-800-FDA-1088.

Megace ES is available by Prescription Only. For full Prescribing Information, click here.

How long should I take Megace ES?

Your healthcare provider will determine how long you should take Megace ES. It is important to follow your healthcare provider’s instructions and keep taking your medication as directed.

What happens if I miss a dose?

If you miss or forget a single dose, continue with your next planned dose on the next day.

What results can I expect from Megace ES?

As with most medicines, individuals can respond differently. In clinical studies, patients had an increase in their appetite, an increase in the amount of calories they ate, and an increase in body weight.¹ They also experienced an improved sense of well-being. These improvements can happen in a few weeks or over a few months. It is important to take Megace ES for as long as directed by your healthcare provider.