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NanoCrystal® Technology of Megace ES NanoCrystal® Technology Megace ES has improved on the micronized formulation of original formula Megace®* by utilizing NanoCrystal® Technology.4 Through this technology, NanoCrystal® particles are created, which are up to 50 times smaller than the micronized particles in original formula Megace. These small particles are produced and stabilized, resulting in an aqueous dispersion of the drug.4 The resulting dispersion provides increased surface area of the total drug, which leads to more rapid dissolution and increased absorption.4 This improves bioavailability of Megace ES in people who have not eaten and allows for the ability to deliver the drug in a smaller volume per dose compared with original formula Megace.
*Megestrol acetate oral suspension.
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Indication
Megace ES (megestrol acetate) is a concentrated suspension indicated for the treatment of anorexia (loss of appetite),
cachexia (severe malnutrition), or an unexplained, significant weight loss in people with a diagnosis of AIDS.1
Megace ES is available by Prescription Only. For full Prescribing Information, click here.
*Adverse events greater than placebo derived from the comprehensive adverse events table (≥5%) in Megace ES and megestrol acetate oral suspension prescribing information.
NanoCrystal® is a registered trademark of Alkermes Pharma Ireland Limited.